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Catalytic Carbonyl Addition through Transfer Hydrogenation: A Departure from Preformed Organometallic Reagents†

  1. John F. Bower Dr.,
  2. In Su Kim Dr.,
  3. Ryan L. Patman,
  4. Michael J. Krische Prof.

Article first published online: 28 NOV 2008

DOI: 10.1002/anie.200802938

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 48, Issue 1, pages 34–46, December 22, 2008

Additional Information

How to Cite

Bower, John F., Kim, I., Patman, Ryan L. and Krische, Michael J. (2009), Catalytic Carbonyl Addition through Transfer Hydrogenation: A Departure from Preformed Organometallic Reagents. Angew. Chem. Int. Ed., 48: 34–46. doi: 10.1002/anie.200802938

Author Information

  1. University of Texas at Austin, Department of Chemistry and Biochemistry, 1 University Station, A5300, Austin, TX 78712-1167 (USA), Fax: (+1) 512-471-8696

  1. †

    Acknowledgement is made to Merck, Umicore, the Robert A. Welch Foundation, the ACS-GCI Pharmaceutical Roundtable, the Korea Research Foundation (KRF-2007-356-E00037), and the NIH-NIGMS (RO1-GM069445) for support of this research. We thank Dr. Oliver Briel (Umicore) for donation of iridium and ruthenium salts, Prof. Xumu Zhang for donation of (R)-C3-TunePhos, and Drs. Ian Davies, Kevin Campos and Scott Shultz (Merck) for donation of (−)-tmbtp.

Publication History

  1. Issue published online: 18 DEC 2008
  2. Article first published online: 28 NOV 2008
  3. Manuscript Received: 19 JUN 2008

Funded by

  • Merck
  • Umicore
  • Robert A. Welch Foundation
  • ACS-GCI Pharmaceutical Roundtable
  • Korea Research Foundation. Grant Number: KRF-2007-356-E00037
  • NIH-NIGMS. Grant Number: RO1-GM069445

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