We thank Dr. Peter T. Glink for helpful discussions and the National Science Council (Taiwan) for financial support (NSC-95-2113M-002-016-MY3).
Solvent-Free Synthesis of the Smallest Rotaxane Prepared to Date†
Article first published online: 29 AUG 2008
Copyright © 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 47, Issue 39, pages 7475–7478, September 15, 2008
How to Cite
Hsu, C.-C., Chen, N.-C., Lai, C.-C., Liu, Y.-H., Peng, S.-M. and Chiu, S.-H. (2008), Solvent-Free Synthesis of the Smallest Rotaxane Prepared to Date. Angew. Chem. Int. Ed., 47: 7475–7478. doi: 10.1002/anie.200803056
- Issue published online: 9 SEP 2008
- Article first published online: 29 AUG 2008
- Manuscript Received: 25 JUN 2008
- National Science Council (Taiwan). Grant Number: NSC-95-2113M-002-016-MY3
- Diels–Alder reaction;
- host–guest systems;
- solvent-free synthesis
Small is beautiful: The pseudorotaxane formed from dipropargylammonium tetrafluoroborate and the crown ether crown-7 on SiO2 was stoppered with 1,2,4,5-tetrazine in a ball-milling process (see X-ray structure). This new and efficient solvent-free reaction led to the isolation in high yield (81 %) of the smallest rotaxane reported to date.