Controlled Nucleation of DNA Metallization


  • Financial support by the Volkswagen Foundation, the German Research Foundation (DFG) (SFB-486 and SFB-749), and the Cluster of Excellence “Nanosystems Initiative Munich” is gratefully acknowledged. C.T.W. thanks the German Chemical Industry Fund (FCI) for a predoctoral fellowship.


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Silver-plated DNA: The deposit of a thin metal layer on biomolecules, such as DNA, requires the formation of small, “magic-sized” metal nuclei. Through the careful design of a reducing chemical functionality in the form of a dialdehyde, the nucleation process and thus the metallization step can be controlled (see scheme).