Communication

Efficient Aerobic Oxidative Synthesis of 2-Substituted Benzoxazoles, Benzothiazoles, and Benzimidazoles Catalyzed by 4-Methoxy-TEMPO†

  1. Yong-Xing Chen,
  2. Ling-Feng Qian,
  3. Wei Zhang Dr.,
  4. Bing Han Dr.

Article first published online: 29 OCT 2008

DOI: 10.1002/anie.200803381

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 47, Issue 48, pages 9330–9333, November 17, 2008

Additional Information

How to Cite

Chen, Y.-X., Qian, L.-F., Zhang, W. and Han, B. (2008), Efficient Aerobic Oxidative Synthesis of 2-Substituted Benzoxazoles, Benzothiazoles, and Benzimidazoles Catalyzed by 4-Methoxy-TEMPO. Angew. Chem. Int. Ed., 47: 9330–9333. doi: 10.1002/anie.200803381

Author Information

  1. State Key Laboratory of Applied Organic Chemistry and Department of Chemistry, Lanzhou University, 222 Tianshui Street S., Lanzhou 730000 (P. R. China), Fax: (+86) 931-891-2582

  1. †

    We are grateful to the National Natural Science Foundation of China (Grant No. 20472027) for financial support. We also thank Dr. Wei Yu for helpful discussions. TEMPO=2,2,6,6-tetramethyl-1-piperidinyloxy free radical.

Publication History

  1. Issue published online: 12 NOV 2008
  2. Article first published online: 29 OCT 2008
  3. Manuscript Received: 11 JUL 2008

Funded by

  • National Natural Science Foundation of China. Grant Number: 20472027

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Keywords:

  • aerobic oxidation;
  • cyclization;
  • heterocycles;
  • synthetic methods
Thumbnail image of graphical abstract

Setting the TEMPO: The scheme shows the efficient aerobic synthesis of 2-substituted benzoxazoles, benzothiazoles, and benzimidazoles where 4-methoxy-2,2,6,6-tetramethyl-1-piperidinyloxy free radical (4-Methoxy-TEMPO) is used as the catalyst.

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