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A Switchable Biocompatible Polymer Surface with Self-Sterilizing and Nonfouling Capabilities

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  • This work is supported by the Defense Threat Reduction Agency (HDTRA1-07-1-0033) and the Office of Naval Research (N000140410409).

Abstract

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Trap, kill, and release: An antimicrobial cationic surface can effectively kill bacterial cells and switch to a nonfouling zwitterionic surface which releases dead microorganisms upon hydrolysis (see picture). This biocompatible nonfouling surface can prevent further attachment of proteins and microorganisms and the formation of a biofilm on the surface.

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