SEARCH

SEARCH BY CITATION

Keywords:

  • amino acids;
  • amino aldehydes;
  • copper;
  • kinetic resolution;
  • oxidation;
  • synthetic methods
Thumbnail image of graphical abstract

Selective recognition: The first efficient method for the kinetic resolution of racemic amino aldehydes (see scheme, PG=protecting group) is based on a copper(II)/(R,R)-Ph-BOX complex. The coordinated amino aldehydes were transformed into optically active amino acid methyl esters, and the non-coordinated amino aldehydes were converted into optically active amino aldehyde dimethyl acetals.