Radical Allylation with α-Branched Allyl Sulfones


  • N.C. thanks the French Ministère de l'Education Nationale, de la Recherche et de la Technologie for a fellowship.


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Branching out with sulfones: The use of allyl isopropyl sulfones solves the problem of premature isomerization and allows the radical addition of xanthates to α-branched allyl sulfones (see scheme; DCE=1,2-dichloroethane, TMS=trimethylsilyl). Highly functionalized structures can thus be rapidly assembled under mild reaction conditions by using cheap and readily available substrates and reagents.