SEARCH

SEARCH BY CITATION

Keywords:

  • helical structures;
  • macrocycles;
  • nanostructures;
  • protein models;
  • self-assembly

Abstract

Thumbnail image of graphical abstract

Protein roll call: Peptide-based building blocks, in which both an α-helix-forming segment and a β-sheet segment are located within a single macrocyclic structure, self-assemble into α-helix-decorated artificial proteins. This approach provides a starting point for developing artificial proteins that can modulate α-helix-mediated interactions occurring in a multivalent fashion.