Financial support from the DFG (SFB 497 and Ni 291/9) is gratefully acknowledged.
The Green Fluorescent Protein: A Key Tool to Study Chemical Processes in Living Cells†
Article first published online: 16 OCT 2008
Copyright © 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 47, Issue 47, pages 8992–8994, November 10, 2008
How to Cite
Nienhaus, G. Ulrich. (2008), The Green Fluorescent Protein: A Key Tool to Study Chemical Processes in Living Cells. Angew. Chem. Int. Ed., 47: 8992–8994. doi: 10.1002/anie.200804998
- Issue published online: 5 NOV 2008
- Article first published online: 16 OCT 2008
- fluorescent probes;
- imaging agents;
- Nobel Prize;
Strike a light! The discovery, isolation, and development of the green fluorescent protein (GFP) and related proteins has revolutionalized the specific fluorescence labeling of proteins in cells. GFPs, the subject of the 2008 Nobel Prize in Chemistry, even facilitate the imaging of various parts of cells in different colors (see picture).