We would like to thank NSERC for financial support of this work.
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Communication
Spectral Tuning of Azobenzene Photoswitches for Biological Applications†
Article first published online: 15 JAN 2009
DOI: 10.1002/anie.200805013
Copyright © 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Sadovski, O., Beharry, Andrew A., Zhang, F. and Woolley, G. Andrew. (2009), Spectral Tuning of Azobenzene Photoswitches for Biological Applications. Angew. Chem. Int. Ed., 48: 1484–1486. doi: 10.1002/anie.200805013
- †
Publication History
- Issue published online: 30 JAN 2009
- Article first published online: 15 JAN 2009
- Manuscript Revised: 20 NOV 2008
- Manuscript Received: 14 OCT 2008
Funded by
- NSERC
Keywords:
- azo compounds;
- isomerization;
- peptides;
- photoswitches
Abstract
Longer switching wavelengths and good photochemical yields and stabilities of the cis isomers in reducing aqueous environments are achieved by introducing 2,2′-aminoalkyl substituents into 4,4′-diamido-substituted azobenzenes. The products are thus suitable for photocontrol of biomolecular structures in intracellular environments, such as switching between two peptide configurations (see picture).