Communication

Formation of the Pyridazine Natural Product Azamerone by Biosynthetic Rearrangement of an Aryl Diazoketone†

  1. Jaclyn M. Winter1,
  2. Ariane L. Jansma2,
  3. Tracy M. Handel Dr.2,
  4. Bradley S. Moore Dr.1,2

Article first published online: 15 DEC 2008

DOI: 10.1002/anie.200805140

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 48, Issue 4, pages 767–770, January 12, 2009

Additional Information

How to Cite

Winter, Jaclyn M., Jansma, Ariane L., Handel, Tracy M. and Moore, Bradley S. (2009), Formation of the Pyridazine Natural Product Azamerone by Biosynthetic Rearrangement of an Aryl Diazoketone. Angew. Chem. Int. Ed., 48: 767–770. doi: 10.1002/anie.200805140

Author Information

  1. 1

    Scripps Institution of Oceanography, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0204 (USA), Fax: (+1) 858-534-1305 http://moorelab.ucsd.edu

  2. 2

    Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093 (USA)

  1. †

    This work was supported by the California Sea Grant Program (R/NMP-98 to B.S.M.) and by a Ruth L. Kirschstein National Research Service Award to J.M.W. from the NIH Training Program in Marine Biotechnology (GM067550). We thank Dr. W. Fenical, Dr. P. R. Jensen, Dr. H. C. Kwon, and Dr. J. Y. Cho (University of California at San Diego (USA)) for Streptomyces sp. CNQ-766 and standard azamerone, and Dr. R. J. Parry (Rice University (USA)), Dr. T. F. Molinski, Dr. T. A. M. Gulder, and Dr. A. A. Mrse for helpful advice.

Publication History

  1. Issue published online: 5 JAN 2009
  2. Article first published online: 15 DEC 2008
  3. Manuscript Received: 20 OCT 2008

Funded by

  • California Sea Grant Program. Grant Number: R/NMP-98
  • NIH. Grant Number: GM067550

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article with Supporting Information (HTML) Get PDF (338K)

Options for accessing this content:

  • If you have access to this content through a society membership, please first log in to your society website.
  • If you would like institutional access to this content, please recommend the title to your librarian.
  • Login via Athens http://onlinelibrary.wiley.com/athens or other institutional login options http://onlinelibrary.wiley.com/login-options .
  • You can purchase online access to this Article for a 24-hour period (price varies by title)
    • If you already have a Wiley Online Library or Wiley InterScience user account: login above and proceed to purchase the article.
    • New Users: Please register, then proceed to purchase the article.

Please register to:

  • Save publications, articles and searches
  • Get email alerts
  • Get all the benefits mentioned below!

Register now >

View Full Article with Supporting Information (HTML) Get PDF (338K)