Functional Molecular Flasks: New Properties and Reactions within Discrete, Self-Assembled Hosts
Article first published online: 23 APR 2009
Copyright © 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 48, Issue 19, pages 3418–3438, April 27, 2009
How to Cite
Yoshizawa, M., Klosterman, Jeremy K. and Fujita, M. (2009), Functional Molecular Flasks: New Properties and Reactions within Discrete, Self-Assembled Hosts. Angew. Chem. Int. Ed., 48: 3418–3438. doi: 10.1002/anie.200805340
- Issue published online: 23 APR 2009
- Article first published online: 23 APR 2009
- Manuscript Received: 1 NOV 2008
- coordination modes;
- host–guest systems;
- molecular flasks;
- supramolecular chemistry
Insider dealing: Self-assembled hosts applied as “molecular flasks” can alter and control the reactivity and properties of molecules encapsulated within their well-defined, confined spaces. A variety of functional hosts of differing sizes, shapes, and utility have been prepared by using the facile and modular concepts of self-assembly.
The application of self-assembled hosts as “molecular flasks” has precipitated a surge of interest in the reactivity and properties of molecules within well-defined confined spaces. The facile and modular synthesis of self-assembled hosts has enabled a variety of hosts of differing sizes, shapes, and properties to be prepared. This Review briefly highlights the various molecular flasks synthesized before focusing on their use as functional molecular containers—specifically for the encapsulation of guest molecules to either engender unusual reactions or unique chemical phenomena. Such self-assembled cavities now constitute a new phase of chemistry, which cannot be achieved in the conventional solid, liquid, and gas phases.