These authors contributed equally.
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Communication
Interfacing Glycosylated Carbon-Nanotube-Network Devices with Living Cells to Detect Dynamic Secretion of Biomolecules†
Article first published online: 4 MAR 2009
DOI: 10.1002/anie.200805514
Copyright © 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Sudibya, H., Ma, J., Dong, X., Ng, S., Li, L.-J., Liu, X.-W. and Chen, P. (2009), Interfacing Glycosylated Carbon-Nanotube-Network Devices with Living Cells to Detect Dynamic Secretion of Biomolecules. Angew. Chem. Int. Ed., 48: 2723–2726. doi: 10.1002/anie.200805514
- †
supported by A*STAR SERC grant (072 101 0020)
- ‡
These authors contributed equally.
Publication History
- Issue published online: 24 MAR 2009
- Article first published online: 4 MAR 2009
- Manuscript Received: 12 NOV 2008
Funded by
- A*STAR SERC. Grant Number: 072 101 0020
Keywords:
- bionanotechnology;
- biosensors;
- carbohydrates;
- carbon nanotubes
Abstract
A sense of cell-being: Single-walled carbon nanotubes (SWNTs) are functionalized with bioactive monosaccharides to enable their use as biosensors. The glycosylated nanotube network is biocompatible and can interface with living cells (see scheme) to electronically detect biomolecular release with high temporal resolution and high sensitivity.