This work was supported by EU6 project BIOCOATING and PICT-2006-01365 (Max-Planck Society—Argentine SeCyt). We also thank Rona Pitschke and Heike Runge for TEM imaging.
1521-3773/asset/2002_left.gif?v=1&s=ac6b0d94a94d7ce7a210002b8096b42feffc0bcf)
1521-3773/asset/2002_right.gif?v=1&s=451042aa3415ae3ad0729984d26dee1866aca82e)
Communication
Near-IR Remote Release from Assemblies of Liposomes and Nanoparticles†
Article first published online: 27 JAN 2009
DOI: 10.1002/anie.200805572
Copyright © 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Issue
Angewandte Chemie International Edition
Volume 48, Issue 10, pages 1807–1809, February 23, 2009
Additional Information
How to Cite
Volodkin, Dmitry V., Skirtach, Andre G. and Möhwald, H. (2009), Near-IR Remote Release from Assemblies of Liposomes and Nanoparticles. Angew. Chem. Int. Ed., 48: 1807–1809. doi: 10.1002/anie.200805572
- †
Publication History
- Issue published online: 17 FEB 2009
- Article first published online: 27 JAN 2009
- Manuscript Received: 14 NOV 2008
Funded by
- EU
- Max-Planck Society
Keywords:
- controlled release;
- drug delivery;
- encapsulation;
- liposomes;
- nanoparticles
Abstract
Set free by light: Near-IR (NIR) laser-initiated remote release of fluorescent dye from complexes of liposome–gold-nanoparticle aggregates is demonstrated (see fluorescence images). Complexes of the desired size are shown to be a viable approach to the construction of vesicle-based drug-delivery systems with light-triggered remote release characteristics. This opens up a new method to manipulate liposome-based drug-delivery systems in a biocompatible way by using the near-IR spectral range.