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Oxindole Synthesis by Direct Coupling of Cmath image[BOND]H and Cmath image[BOND]H Centers

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  • Support of this work by the Swiss National Foundation is gratefully acknowledged.

Abstract

An sp2/sp3get-together: A novel and efficient method can be used to synthesize 3,3-disubstitued oxindoles by the direct intramolecular oxidative coupling of an aryl Cmath image[BOND]H and a Cmath image[BOND]H center (see scheme; DMF=N,N-dimethylformamide).

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