Fluorescent Color Readout of DNA Hybridization with Thiazole Orange as an Artificial DNA Base


  • Financial support by the the Deutsche Forschungsgemeinschaft, the Fonds der Chemischen Industrie, and the University of Regensburg is gratefully acknowledged.


A fluorescent chameleon: A single thiazole orange (TO) dye, when used as an artificial DNA base shows the typical green emission, whereas the interstrand TO dimer exhibits an orange excimer-type emission inside duplex DNA (see picture).

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