Platinum(II)-Catalyzed Intramolecular Cyclization of o-Substituted Aryl Alkynes through sp3 C[BOND]H Activation

Authors


  • This work was supported by the University of Chicago. We thank Dr. J. Halpern for the generous gift of Pt salts.

Abstract

Ring leader: PtCl2 catalyzes intramolecular cyclization of o-isopropyl or o-benzyl aryl alkynes to give substituted indene derivatives with good yields and high selectivity. This reaction appears to proceed through an sp3 C[BOND]H activation and 1,4-hydrogen migration pathway (see scheme).

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