Copyright© The Nobel Foundation 2008. We thank the Nobel Foundation, Stockholm, for permission to print this lecture.
Constructing and Exploiting the Fluorescent Protein Paintbox (Nobel Lecture)†
Article first published online: 29 JUN 2009
Copyright © 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 48, Issue 31, pages 5612–5626, July 20, 2009
How to Cite
Tsien, Roger Y. (2009), Constructing and Exploiting the Fluorescent Protein Paintbox (Nobel Lecture). Angew. Chem. Int. Ed., 48: 5612–5626. doi: 10.1002/anie.200901916
- Issue published online: 15 JUL 2009
- Article first published online: 29 JUN 2009
- Manuscript Received: 8 APR 2009
- fluorescent proteins;
- in vivo imaging;
- Nobel Lecture
Trip the light fantastic: The green fluorescent protein (GFP) is an invaluable tool for biochemical and medicinal research. It can make tumors, amyloid plaques from Alzheimer′s disease, or pathogenic bacteria equally visible. Ground-breaking contributions in this field have resulted in the 2008 Nobel Prize for Chemistry being awarded to Osamu Shimomura, Martin Chalfie, and Roger Tsien. The Nobel Laureates describe their research first-hand.