Communication

Macrocyclization by Nickel-Catalyzed, Ester-Promoted, Epoxide–Alkyne Reductive Coupling: Total Synthesis of (−)-Gloeosporone†

  1. James D. Trenkle Dr.1,2,
  2. Timothy F. Jamison Prof. Dr.1

Article first published online: 17 JUN 2009

DOI: 10.1002/anie.200902079

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 48, Issue 29, pages 5366–5368, July 6, 2009

Additional Information

How to Cite

Trenkle, James D. and Jamison, Timothy F. (2009), Macrocyclization by Nickel-Catalyzed, Ester-Promoted, Epoxide–Alkyne Reductive Coupling: Total Synthesis of (−)-Gloeosporone. Angew. Chem. Int. Ed., 48: 5366–5368. doi: 10.1002/anie.200902079

Author Information

  1. 1

    Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139 (USA), Fax: (+1) 617-324-0253 http://web.mit.edu/chemistry/jamison

  2. 2

    Current address: Gilead Sciences, 333 Lakeside Dr., Foster City, CA 94404 (USA)

  1. †

    Support for this work was provided by the National Institute of General Medical Sciences (GM-72566). We are grateful to Li Li for obtaining mass spectrometric data for all compounds (MIT Department of Chemistry Instrumentation Facility, which is supported in part by the NSF (CHE-9809061 and DBI-9729592) and the NIH (1S10RR13886-01)).

Publication History

  1. Issue published online: 1 JUL 2009
  2. Article first published online: 17 JUN 2009
  3. Manuscript Received: 17 APR 2009

Funded by

  • National Institute of General Medical Sciences. Grant Number: GM-72566
  • NSF. Grant Numbers: CHE-9809061, DBI-9729592
  • NIH. Grant Number: 1S10RR13886-01

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