Immediate Detection of Living Bacteria at Ultralow Concentrations Using a Carbon Nanotube Based Potentiometric Aptasensor


  • We would like to thank A. Maroto and R. Villamizar for their helpful comments and also S. Moreno for the loan of essential equipment. This study has been supported by the Spanish Ministry of Education and Science, MEC, through the project grants NAN2004-09306-C05-05 and CTQ2007-67570/BQU. G.A.Z.-G. would like to thank the Generalitat de Catalunya (Catalan Government) and European Social Fund for awarding the FI DGR fellowship.


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Keeping the doctor away: An aptamer attached to an electrode coated with single-walled carbon nanotubes interacts selectively with bacteria (see picture). The resulting electrochemical response is highly accurate and reproducible and starts at ultralow bacteria concentrations, thus providing a simple, selective method for pathogen detection.