UMN Undergraduate Research, 2007–2008.
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Communication
Chemoselectivity in Catalytic C![[BOND]](http://onlinelibrarystatic.wiley.com/undisplayable_characters/00f8ff.gif)
C and CH Bond Activation: Controlling Intermolecular Carboacylation and Hydroarylation of Alkenes†
Article first published online: 9 JUL 2009
DOI: 10.1002/anie.200902215
Copyright © 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Wentzel, M., Reddy, V., Hyster, T. and Douglas, C. (2009), Chemoselectivity in Catalytic CC and CH Bond Activation: Controlling Intermolecular Carboacylation and Hydroarylation of Alkenes. Angewandte Chemie International Edition, 48: 6121–6123. doi: 10.1002/anie.200902215
- †
We acknowledge the donors of the ACS Petroleum Research Fund for partial support (47565-G1). We thank Dr. Letitia Yao (NMR spectroscopy), Matthew Meyer and Jacob Schmidt (mass spectrometry), and UMN (start-up funds).
Publication History
- Issue published online: 29 JUL 2009
- Article first published online: 9 JUL 2009
- Manuscript Received: 25 APR 2009
Funded by
- ACS Petroleum Research Fund. Grant Number: 47565-G1
Keywords:
- CC activation;
- CH activation;
- chemoselectivity;
- homogeneous catalysis;
- rhodium
Graphical Abstract
It's all under control: The selection between CC and CH activation pathways in 8-acylquinolines can be influenced by the choice of catalyst and solvent (see scheme; cod=cycloocta-1,5-diene). In this approach, an unstrained CC σ bond is activated and subsequent intermolecular carboacylation of an olefin results in the formation of two new CC σ bonds.