Meta-Selective Transition-Metal Catalyzed Arene C[BOND]H Bond Functionalization


  • We thank the NSFC (No. 20802040) for financial support.


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The selectivity is meta! Recent developments on transition-metal catalyzed meta-selective C[BOND]H functionalization are highlighted (see scheme; EDG=electron-donating group, EWG=electron-withdrawing group). The method is complementary to traditional methodologies and might provide numerous opportunities to access previously difficult organic products. Possible mechanisms are discussed.