Biomimetic Encapsulation of Individual Cells with Silica


  • This work was supported by the Korea Research Foundation Grant funded by the Korean Government (MOEHRD) (KRF-2008-313-C00496) and the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (2009-0083525). We thank M. S. Hyun and M. H. Kim at the National Nanofab Center for the SEM and EDX analyses and Dr. H. S. Kweon and H. J. Cho at KBSI for the TEM analyses. We also thank Y. M. Lee at KAIST and Y. J. Shim at Chungnam National University for the cell culture.


original image

Yeast wears a silica coat: Various living cells were individually coated with silica using layer-by-layer self-assembly and biomimetic silicification (see picture). The viability of yeast cells was found to be enhanced threefold after silica encapsulation, and their cell division could be suppressed by encapsulation.