Communication

Specificity and Mechanism of Acinetobacter baumanii Nicotinamidase: Implications for Activation of the Front-Line Tuberculosis Drug Pyrazinamide†

  1. Paul K. Fyfe Dr.,
  2. Vincenzo A. Rao,
  3. Aleksandra Zemla,
  4. Scott Cameron Dr.,
  5. William N. Hunter Prof.

Article first published online: 26 OCT 2009

DOI: 10.1002/anie.200903407

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 48, Issue 48, pages 9176–9179, November 16, 2009

Additional Information

How to Cite

Fyfe, Paul K., Rao, Vincenzo A., Zemla, A., Cameron, S. and Hunter, William N. (2009), Specificity and Mechanism of Acinetobacter baumanii Nicotinamidase: Implications for Activation of the Front-Line Tuberculosis Drug Pyrazinamide. Angew. Chem. Int. Ed., 48: 9176–9179. doi: 10.1002/anie.200903407

Author Information

  1. Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH (UK), Fax: (+44) 1382-385764

  1. †

    Funded by the BBSRC [BBS/B/14434], The Wellcome Trust [082596 and 083481] and EC Seventh Framework Programme (FP7/2007-2013). We thank Lorna Eades of the University of Edinburgh, Mark Agacan, the Diamond Synchrotron Radiation Facility and the European Synchrotron Radiation facility for support.

Publication History

  1. Issue published online: 11 NOV 2009
  2. Article first published online: 26 OCT 2009
  3. Manuscript Revised: 24 AUG 2009
  4. Manuscript Received: 23 JUN 2009

Funded by

  • BBSRC. Grant Number: BBS/B/14434
  • The Wellcome Trust. Grant Numbers: 082596, 083481
  • EC Seventh Framework Programme. Grant Number: FP7/2007-2013

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