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Supramolecular Catalyst for Aldehyde Hydrogenation and Tandem Hydroformylation–Hydrogenation


  • This research was supported by the DFG, the International Research Training Group “Catalysts and Catalytic Reactions for Organic Synthesis” (IRTG 1038), the Fonds der Chemischen Industrie, BASF, and Wacker (donation of chemicals).


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The chemoselective reduction of aldehydes and the tandem hydroformylation–hydrogenation of terminal alkenes are possible with a supramolecular catalyst that operates by a novel mechanism involving substrate activation by hydrogen bonding and subsequent metal–ligand bifunctional hydrogenation (see scheme).

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