Communication

Application of Fragment Growing and Fragment Linking to the Discovery of Inhibitors of Mycobacterium tuberculosis Pantothenate Synthetase†

  1. Alvin W. Hung1,
  2. H. Leonardo Silvestre2,
  3. Shijun Wen Dr.1,
  4. Alessio Ciulli Dr.1,
  5. Tom L. Blundell Prof.2,
  6. Chris Abell Prof.1

Article first published online: 24 SEP 2009

DOI: 10.1002/anie.200903821

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 48, Issue 45, pages 8452–8456, October 26, 2009

Additional Information

How to Cite

Hung, Alvin W., Silvestre, H. Leonardo., Wen, S., Ciulli, A., Blundell, Tom L. and Abell, C. (2009), Application of Fragment Growing and Fragment Linking to the Discovery of Inhibitors of Mycobacterium tuberculosis Pantothenate Synthetase. Angew. Chem. Int. Ed., 48: 8452–8456. doi: 10.1002/anie.200903821

Author Information

  1. 1

    Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW (UK), Fax: (+44) 1223-336-362 http://www.ch.cam.ac.uk/staff/ca.html

  2. 2

    Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA (UK)

  1. †

    This research was supported by the Bill & Melinda Gates Foundation. We are also grateful for funding from the Agency for Science Technology and Research (A*star) Singapore (PhD sponsorship, A.W.H.), the Fundacao para a Ciencia e Tecnologia (FCT; PhD sponsorship, H.L.S.), and Homerton College (Junior Research Fellowship to A.C.).

Publication History

  1. Issue published online: 20 OCT 2009
  2. Article first published online: 24 SEP 2009
  3. Manuscript Received: 13 JUL 2009

Funded by

  • Bill & Melinda Gates Foundation
  • Agency for Science Technology and Research (A*star)

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