This work was financially supported by Grants-in-Aid for Scientific Research (S) (no. 17105003, YN), for Young Scientists (B) (no. 27150173, JGL) from JSPS, on Priority Areas (no. 19027044, YN), Innovative Areas (no. 20200050, JGL) from MEXT; and by the Elemental Science and Technology Project from MEXT. The 430 nm laser was set up by Dr. Ken’ichi Nakagawa, The University of Electro-Communications (Japan).
Spectroscopic Characterization of a Hydroperoxo–Heme Intermediate: Conversion of a Side-On Peroxo to an End-On Hydroperoxo Complex†
Article first published online: 30 OCT 2009
Copyright © 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 48, Issue 49, pages 9262–9267, November 23, 2009
How to Cite
Liu, J.-G., Ohta, T., Yamaguchi, S., Ogura, T., Sakamoto, S., Maeda, Y. and Naruta, Y. (2009), Spectroscopic Characterization of a Hydroperoxo–Heme Intermediate: Conversion of a Side-On Peroxo to an End-On Hydroperoxo Complex. Angew. Chem. Int. Ed., 48: 9262–9267. doi: 10.1002/anie.200904572
- Issue published online: 17 NOV 2009
- Article first published online: 30 OCT 2009
- Manuscript Received: 17 AUG 2009
- bioinorganic chemistry;
- enzyme models;
- heme proteins;
- OO activation
Modeling job: Protonation of a closed seven-coordinate side-on heme peroxide can switch its spin state from high- to low-spin and convert the η2 binding fashion into a monodentate configuration to afford the corresponding hydroperoxide (see scheme). The end-on low-spin ferric hydroperoxo–heme species bear a covalently appended axial imidazole ligand and are easily prepared.