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A Multinuclear Coordination System of L-Cysteine and L-Penicillamine That Induce Opposite Chiralities at Metal Centers
Article first published online: 2 OCT 2009
DOI: 10.1002/anie.200904635
Copyright © 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
1521-3773/asset/cover.gif?v=1&s=412bc65bdcb3f0e34a94f27c1c13e908726694d4 "Angewandte Chemie International Edition")
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How to Cite
Sameshima, Y., Yoshinari, N., Tsuge, K., Igashira-Kamiyama, A. and Konno, T. (2009), A Multinuclear Coordination System of L-Cysteine and L-Penicillamine That Induce Opposite Chiralities at Metal Centers. Angew. Chem. Int. Ed., 48: 8469–8472. doi: 10.1002/anie.200904635
Publication History
- Issue published online: 20 OCT 2009
- Article first published online: 2 OCT 2009
- Manuscript Received: 20 AUG 2009
Keywords:
- amino acids;
- chirality;
- coordination modes;
- S ligands;
- transition metals
Same but different: L-Cysteine (L-cys) and L-penicillamine (L-pen) ligands are incorporated in similar pentanuclear AuI3M2 (M=NiII, CoIII) structures with, however, opposite stereochemical configurations. This phenomenon is explained in terms of intramolecular hydrogen bonding and steric interactions, which may provide insight into why D-penicillamine behaves like L-cysteine in nature.