We thank the NSF of China (20633030, 20721063, and 20873026), the State Key Basic Research Program of PRC (2009CB623506), the Science & Technology Commission of Shanghai Municipality (08DZ2270500, 07QH14003), and the Shanghai Education Committee (06SG03) for financial support.
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Communication
Efficient and Selective Room-Temperature Gold-Catalyzed Reduction of Nitro Compounds with CO and H2O as the Hydrogen Source†
Article first published online: 17 NOV 2009
DOI: 10.1002/anie.200904647
Copyright © 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
He, L., Wang, L.-C., Sun, H., Ni, J., Cao, Y., He, H.-Y. and Fan, K.-N. (2009), Efficient and Selective Room-Temperature Gold-Catalyzed Reduction of Nitro Compounds with CO and H2O as the Hydrogen Source. Angew. Chem. Int. Ed., 48: 9538–9541. doi: 10.1002/anie.200904647
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Publication History
- Issue published online: 30 NOV 2009
- Article first published online: 17 NOV 2009
- Manuscript Revised: 14 OCT 2009
- Manuscript Received: 20 AUG 2009
Funded by
- NSF of China. Grant Numbers: 20633030, 20721063, 20873026
- State Key Basic Research Program of PRC. Grant Number: 2009CB623506
- Science & Technology Commission of Shanghai Municipality. Grant Numbers: 08DZ2270500, 07QH14003
- Shanghai Education Committee. Grant Number: 06SG03
Keywords:
- chemoselectivity;
- gold;
- nitro compounds;
- reduction;
- sustainable chemistry
Taking hydrogen from water: Gold catalysis enabled the selective reduction of nitro compounds under very mild conditions with a combination of H2O and CO as the reductant (see scheme). This environmentally friendly reaction proceeded in high yield and with high chemoselectivity in the presence of a wide range of functional groups.