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Keywords:

  • asymmetric synthesis;
  • carboxylation;
  • esterification;
  • silacarboxylic acids;
  • silanes
Thumbnail image of graphical abstract

Sila analogues: The first asymmetric synthesis of silacarboxylic acids with a stereogenic center at the silicon atom has been achieved from chiral nonracemic silanols, without loss of optical purity. Silacarboxylic acids can be converted into their corresponding esters using a Mitsunobu-type reaction.