J.Z. acknowledges support from the National Natural Science Foundation of China (20604011, 20974044, 90923006), National Basic Research Program of China (2007CB925103), New Century Excellent Talents Program in University (NCET-06-0451), and Six-Profession Talents Summit Program of Jiangsu Province (06-A-018).
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Communication
Nanoparticle-Based, Fluorous-Tag-Driven DNA Detection†
Article first published online: 12 NOV 2009
DOI: 10.1002/anie.200905267
Copyright © 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Hong, M., Zhou, X., Lu, Z. and Zhu, J. (2009), Nanoparticle-Based, Fluorous-Tag-Driven DNA Detection. Angew. Chem. Int. Ed., 48: 9503–9506. doi: 10.1002/anie.200905267
- †
Publication History
- Issue published online: 30 NOV 2009
- Article first published online: 12 NOV 2009
- Manuscript Received: 21 SEP 2009
Funded by
- National Natural Science Foundation of China. Grant Numbers: 20604011, 20974044, 90923006
- National Basic Research Program of China. Grant Number: 2007CB925103
- New Century Excellent Talents Program in University. Grant Number: NCET-06-0451
- Six-Profession Talents Summit Program of Jiangsu Province. Grant Number: 06-A-018
Keywords:
- DNA detection;
- fluorous tags;
- nanoparticles;
- gold;
- interfaces
Tagging along: A DNA detection method has been developed that relies on the interfacial assembly of gold nanoparticles. The fluorous-tag-driven formation of nanoparticle networks (see scheme) at the gas/liquid, liquid/liquid, or solid/liquid interface is such that a single type of assembly architecture is suitable for an array of detection formats.