We thank the U.S. National Science Foundation for support of this work through grant CHE-0718117.
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Asymmetric Synthesis of Chiral Tetraphenylenes†
Article first published online: 22 DEC 2009
DOI: 10.1002/anie.200905421
Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Rajca, A. and Rajca, S. (2010), Asymmetric Synthesis of Chiral Tetraphenylenes. Angewandte Chemie International Edition, 49: 672–674. doi: 10.1002/anie.200905421
- †
Publication History
- Issue published online: 13 JAN 2010
- Article first published online: 22 DEC 2009
- Manuscript Received: 28 SEP 2009
Funded by
- National Science Foundation. Grant Number: CHE-0718117
- Abstract
- Article
- References
- Cited By
Keywords:
- asymmetric synthesis;
- chirality;
- cycloaddition;
- racemization;
- tetraphenylenes
Graphical Abstract
Intriguing scaffolds: Tetraphenylenes with symmetry-breaking substitution have chiral π systems and extraordinarily high barriers for racemization. Their applications as building blocks for chiral materials and as ligands in asymmetric synthesis are hindered by the difficulty in obtaining the chiral tetraphenylene core. Rhodium-catalyzed [2+2+2] cycloadditions of triynes provide an effective alternative synthesis.