Efficient Synthesis of Aryl Fluorides


  • This work was funded by the Alexander-von-Humboldt-Stiftung, the State of Mecklenburg-Western Pomerania, the BMBF, and the DFG (Leibniz Prize). We thank S. Leiminger (LIKAT) for analytical support.


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Creating C[BOND]F bonds: A novel electrophilic fluorination of aryl and heteroaryl Grignard reagents has been discovered and was used for the efficient synthesis of various aryl fluoride derivatives (see picture; THF=tetrahydrofuran).