Y.Y. thanks the University of California, Riverside for start-up funds. Acknowledgement is also given to the Donors of the Petroleum Research Fund, administered by the American Chemical Society, for support of this research. Y.Y. is a Cottrell Scholar of Research Corporation for Science Advancement.
Self-Assembled TiO2 Nanocrystal Clusters for Selective Enrichment of Intact Phosphorylated Proteins†
Article first published online: 12 FEB 2010
Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 49, Issue 10, pages 1862–1866, March 1, 2010
How to Cite
Lu, Z., Ye, M., Li, N., Zhong, W. and Yin, Y. (2010), Self-Assembled TiO2 Nanocrystal Clusters for Selective Enrichment of Intact Phosphorylated Proteins. Angew. Chem. Int. Ed., 49: 1862–1866. doi: 10.1002/anie.200906648
- Issue published online: 22 FEB 2010
- Article first published online: 12 FEB 2010
- Manuscript Received: 25 NOV 2009
- University of California, Riverside
- Petroleum Research Fund
- mesoporous materials;
Mesoporous traps: The title clusters were fabricated through self-assembly of nanocrystals in emulsion droplets and subsequent protective calcination. The specific affinity offered by the metal oxide and the size-exclusion mechanism enabled by the mesoporous structure enable the use of these clusters for efficient enrichment of intact phosphorylated proteins from complex biological samples (see picture).