Preparation of Photoluminescent Nanorings with Controllable Bioreducibility and Stimuli-Responsiveness

Authors

  • Ye-Zi You Prof. Dr.,

    1. CAS Key Lab of Soft Matter Chemistry Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, 230026, Anhui (China), Fax: (+86) 551-360-1592
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  • Zhi-Qiang Yu,

    1. CAS Key Lab of Soft Matter Chemistry Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, 230026, Anhui (China), Fax: (+86) 551-360-1592
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  • Meng-Meng Cui,

    1. CAS Key Lab of Soft Matter Chemistry Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, 230026, Anhui (China), Fax: (+86) 551-360-1592
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  • Chun-Yan Hong Prof. Dr.

    1. CAS Key Lab of Soft Matter Chemistry Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, 230026, Anhui (China), Fax: (+86) 551-360-1592
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  • The authors thank the Nation Science Foundation of China (20874093, 50973102 and 20674077) and Ministry of Science and Technology of China (2010CB934000) for financial support.

Abstract

original image

Ring around the rosy: A novel multifunctional disulfide-containing hyperbranched poly(amido amine) that is stimuli-responsive, biocompatible, biodegradable, and photoluminescent can assemble DNA into a well-defined nanoring with strong photoluminescence. The nanoring is stimuli-responsive and the ring wall is biocompatible and controllably bioreducible; it has potential applications in gene and drug delivery, and molecular imaging.

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