Inside Cover

Inside Cover: A Synthetic Lectin for O-Linked β-N-Acetylglucosamine (Angew. Chem. Int. Ed. 10/2009)

  1. Yann Ferrand Dr.1,
  2. Emmanuel Klein Dr.1,
  3. Nicholas P. Barwell1,
  4. Matthew P. Crump Dr.1,
  5. Jesus Jiménez-Barbero Prof.2,
  6. Cristina Vicent Dr.3,
  7. Geert-Jan Boons Prof.4,
  8. Sampat Ingale4,
  9. Anthony P. Davis Prof.1

Article first published online: 17 FEB 2009

DOI: 10.1002/anie.200990042

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 48, Issue 10, page 1698, February 23, 2009

Additional Information

How to Cite

Ferrand, Y., Klein, E., Barwell, Nicholas P., Crump, Matthew P., Jiménez-Barbero, J., Vicent, C., Boons, G.-J., Ingale, S. and Davis, Anthony P. (2009), Inside Cover: A Synthetic Lectin for O-Linked β-N-Acetylglucosamine (Angew. Chem. Int. Ed. 10/2009). Angew. Chem. Int. Ed., 48: 1698. doi: 10.1002/anie.200990042

Author Information

  1. 1

    School of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS (UK), Fax: (+44) 117-929-8611

  2. 2

    Centro de Investigaciones Biológicas, CSIC, Madrid (Spain)

  3. 3

    Instituto de Química Organica, CSIC, Madrid (Spain)

  4. 4

    Complex Carbohydrate Research Center, University of Georgia (USA)

Publication History

  1. Issue published online: 17 FEB 2009
  2. Article first published online: 17 FEB 2009

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Keywords:

  • biomimetic hosts;
  • carbohydrates;
  • molecular recognition;
  • receptors;
  • supramolecular chemistry

Abstract

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Carbohydrates are slippery customers in water. Camouflaged by solvent-mimicking hydroxy groups, they make challenging targets, even for natural receptors. In their Communication on page 1775 ff., A. P. Davis and co-workers describe a synthetic receptor that is remarkably effective for the important β-N-acetylglucosaminyl (β-GlcNAC) unit. The affinities of the receptor are good and its selectivities are excellent, even by the standards of natural carbohydrate-binding proteins.

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