We are grateful for the financial support provided by the Basic Research Program (973 Program) of China (grant no. 2010CB833203) and the National Natural Science Foundation of China (grant nos. 20621091 and 20772050). We thank Mingji Dai (Columbia University) for helpful discussions.
Construction of Two Vicinal Quaternary Carbons by Asymmetric Allylic Alkylation: Total Synthesis of Hyperolactone C and (−)-Biyouyanagin A†
Article first published online: 17 NOV 2009
Copyright © 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 48, Issue 49, page 9211, November 23, 2009
How to Cite
- Issue published online: 17 NOV 2009
- Article first published online: 17 NOV 2009
Vol. 48, Issue 42, 7853–7856, Article first published online: 11 SEP 2009
- asymmetric allylic alkylation;
- natural products;
- quaternary carbon centers
In this Communication, the discussion of work by the Kraus research group was not precisely expressed and should be corrected to the following: Kraus and Wei[3d] reported that 7 and its diastereomer, which were claimed to be isolated as by-products in their elegant synthesis of racemic hyperolactone C, could not be converted into a lactone using heat, acid (PTSA), or base (tBuOK, NaH, or KH) catalysis. However, careful analysis and comparison of the NMR data of 13 (1:1 mixture of diastereomers) with both the by-products reported by Kraus and Wei indicated that they were identical (see the Supporting Information).
Moreover, the value of δ=155.9 ppm in the 13C NMR data listed for compound 13 in the Supporting Information should be removed. The authors are grateful to Prof. David Hodgson of Oxford University for pointing this out.