This research was supported by NIH-NCI NanoSystems Biology Cancer Center (U54CA119347).
Photothermal Effects of Supramolecularly Assembled Gold Nanoparticles for the Targeted Treatment of Cancer Cells†
Article first published online: 9 APR 2010
Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 49, Issue 22, pages 3777–3781, May 17, 2010
How to Cite
Wang, S., Chen, K.-J., Wu, T.-H., Wang, H., Lin, W.-Y., Ohashi, M., Chiou, P.-Y. and Tseng, H.-R. (2010), Photothermal Effects of Supramolecularly Assembled Gold Nanoparticles for the Targeted Treatment of Cancer Cells. Angew. Chem. Int. Ed., 49: 3777–3781. doi: 10.1002/anie.201000062
- Issue published online: 10 MAY 2010
- Article first published online: 9 APR 2010
- Manuscript Received: 6 JAN 2010
- NCI. Grant Number: U54CA119347
- photothermal effects;
- tumor therapy
Laser-triggered nanobomb: Size-controlled gold supramolecular nanoparticles (Au-SNPs) were synthesized from 2 nm gold colloids by a supramolecular self-assembly approach. These Au-SNPs exhibited significantly enhanced photothermal effects and could be used in conjunction with laser irradiation for the selective destruction of cancer cells (see picture) after the incorporation of a target-specific ligand.