Photothermal Effects of Supramolecularly Assembled Gold Nanoparticles for the Targeted Treatment of Cancer Cells


  • This research was supported by NIH-NCI NanoSystems Biology Cancer Center (U54CA119347).


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Laser-triggered nanobomb: Size-controlled gold supramolecular nanoparticles (Au-SNPs) were synthesized from 2 nm gold colloids by a supramolecular self-assembly approach. These Au-SNPs exhibited significantly enhanced photothermal effects and could be used in conjunction with laser irradiation for the selective destruction of cancer cells (see picture) after the incorporation of a target-specific ligand.