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Cover Picture: Wacker-Type Oxidation of Internal Olefins Using a PdCl2/N,N-Dimethylacetamide Catalyst System under Copper-Free Reaction Conditions (Angew. Chem. Int. Ed. 7/2010)



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A Wacker-type oxidation of internal olefins into ketones is described by K. Kaneda and co-workers in their Communication on page 1238 ff. The reaction proceeds under an atmosphere of O2 in the presence of a homogeneous palladium catalyst with water as the oxygen source. Artistically, the reaction is depicted as moving through an hour glass as the reactants are transformed into product.