Get access

Glucose Activation by Transient Cr2+ Dimers

Authors

  • Evgeny A. Pidko Dr.,

    1. Schuit Institute of Catalysis, Eindhoven University of Technology, P.O. Box 513, NL-5600 MB, Eindhoven (The Netherlands), Fax: (+31) 40-245-5054
    Search for more papers by this author
  • Volkan Degirmenci Dr.,

    1. Schuit Institute of Catalysis, Eindhoven University of Technology, P.O. Box 513, NL-5600 MB, Eindhoven (The Netherlands), Fax: (+31) 40-245-5054
    Search for more papers by this author
  • Rutger A. van Santen Prof. Dr.,

    1. Schuit Institute of Catalysis, Eindhoven University of Technology, P.O. Box 513, NL-5600 MB, Eindhoven (The Netherlands), Fax: (+31) 40-245-5054
    Search for more papers by this author
  • Emiel J. M. Hensen Prof. Dr.

    1. Schuit Institute of Catalysis, Eindhoven University of Technology, P.O. Box 513, NL-5600 MB, Eindhoven (The Netherlands), Fax: (+31) 40-245-5054
    Search for more papers by this author

  • This research was performed within the framework of the CatchBio program. We gratefully acknowledge the support of the Smart Mix Program of the Netherlands Ministry of Economic Affairs and the Netherlands Ministry of Education, Culture and Science. E.J.M.H. and V.D. thank the Technology Foundation STW, the applied-science division of NWO. NWO-NCF and NWO-Dubble are acknowledged for access to computing and XAS facilities, respectively.

Abstract

original image

Cat waiting in the wings: The transient formation of Cr2+ dimers through coordination to a second molecule of the catalyst promotes the isomerization of glucose to fructose and explains the unique ability of CrCl2 to catalyze the dehydration of glucose to 5-hydroxymethylfurfural (HMF) in ionic-liquid media. The active-site environment during the rate-controlling step resembles that in hexose isomerase enzymes.

Ancillary