Communication

Bright Three-Photon Luminescence from Gold/Silver Alloyed Nanostructures for Bioimaging with Negligible Photothermal Toxicity†

  1. Ling Tong2,
  2. Claire M. Cobley1,
  3. Jingyi Chen Dr.1,
  4. Younan Xia Prof.1,
  5. Ji-Xin Cheng Prof.2,3

Article first published online: 6 APR 2010

DOI: 10.1002/anie.201000440

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 49, Issue 20, pages 3485–3488, May 3, 2010

Additional Information

How to Cite

Tong, L., Cobley, Claire M., Chen, J., Xia, Y. and Cheng, J.-X. (2010), Bright Three-Photon Luminescence from Gold/Silver Alloyed Nanostructures for Bioimaging with Negligible Photothermal Toxicity. Angew. Chem. Int. Ed., 49: 3485–3488. doi: 10.1002/anie.201000440

Author Information

  1. 1

    Department of Biomedical Engineering, Washington University, Saint Louis, MO 63130 (USA), Fax: (+1) 314-935-7448

  2. 2

    Department of Chemistry, Purdue University, West Lafayette, IN 47907 (USA), Fax: (+1) 765-496-1902

  3. 3

    Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907 (USA)

  1. †

    This work was supported in part by an NSF grant (CBET-0828832) to J.X.C., an AHA predoctoral fellowship to L.T., and a 2006 NIH Director’s Pioneer Award (DP1 OD000798) to Y.X.

Publication History

  1. Issue published online: 28 APR 2010
  2. Article first published online: 6 APR 2010
  3. Manuscript Revised: 2 MAR 2010
  4. Manuscript Received: 25 JAN 2010

Funded by

  • NSF. Grant Number: CBET-0828832
  • NIH Director’s Pioneer Award. Grant Number: DP1 OD000798

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article with Supporting Information (HTML) Get PDF (729K)

Keywords:

  • biosensors;
  • luminescence;
  • nanostructures;
  • near-infrared imaging;
  • photothermal toxicity
Thumbnail image of graphical abstract

Au/Ag alloyed nanostructures exhibit a bright three-photon luminescence (3PL; see picture, left) upon excitation by a femtosecond laser at 1290 nm, with an intensity level one order of magnitude higher than pure Au or Ag nanoparticles. As the excitation is outside the range of plasmon resonance, 3PL enables bioimaging (right) with negligible photothermal toxicity.

View Full Article with Supporting Information (HTML) Get PDF (729K)