This work is part of the Coral Reef Initiative in the South Pacific (grant CZZ 3012.01 T, AFD). We thank the Solomon Islands Government for collection permits, the Fisheries Department and R. Sulu (University of the South Pacific) for their help and assistance, the field team of the IRD-Nouméa for the collection of the sponge, and John Hooper (Queensland Museum, Brisbane) for the identification of the sample.
Unprecedented Stylissazoles A–C from Stylissa carteri: Another Dimension for Marine Pyrrole-2-aminoimidazole Metabolite Diversity†
Article first published online: 31 MAY 2010
Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 49, Issue 28, pages 4775–4779, June 28, 2010
How to Cite
Patel, K., Laville, R., Martin, M.-T., Tilvi, S., Moriou, C., Gallard, J.-F., Ermolenko, L., Debitus, C. and Al-Mourabit, A. (2010), Unprecedented Stylissazoles A–C from Stylissa carteri: Another Dimension for Marine Pyrrole-2-aminoimidazole Metabolite Diversity. Angew. Chem. Int. Ed., 49: 4775–4779. doi: 10.1002/anie.201000444
- Issue published online: 21 JUN 2010
- Article first published online: 31 MAY 2010
- Manuscript Revised: 19 APR 2010
- Manuscript Received: 25 JAN 2010
- Coral Reef Initiative in the South Pacific. Grant Number: CZZ 3012.01 T
- structure elucidation
No cramping this “styl”: The three title compounds, dimeric pyrrole-2-aminoimidazole alkaloids, were isolated from the marine sponge Stylissa carteri collected in the Solomon Islands. The isolated compounds are exclusively NC-bonded “dimers”, which indicates a different mode of dimerization and adds another dimension to the molecular diversity of pyrrole-2-aminoimidazole alkaloids.