Glandular Trichomes of Leucosceptrum canum Harbor Defensive Sesterterpenoids

Authors


  • This research was supported financially by the “Hundred Talents Program” of the Chinese Academy of Sciences (CAS), the National Natural Science Foundation of China, the State Key Laboratory of Phytochemistry and Plant Resources in West China (P2009-ZZ01 and P2008-ZZ18), the Germplasm Bank of Wild Species, and the CAS Innovation Program of Kunming Institute of Botany (540806321211, 07067722K1, and 07067712K1). We thank Prof. Ji-Kai Liu and Prof. Han-Dong Sun for valuable suggestions on the whole research, Prof. Qi-Tai Zheng and Prof. Ren-Wang Jiang for helpful discussions on the X-ray crystal structure of compound 1, and Zong-Xin Ren for assistance in the collection of plant material.

Abstract

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On the defense: Sesterterpenoid 1 and its 11-dehydroxy derivative, which possess a unique C25 skeleton, have been isolated from the glandular trichomes of Leucosceptrum canum. They have potent antifeedant activities and inhibitory effects against pathogenic fungi, which suggest a role of sesterterpenoids in plant defense.

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