An unfolding story: Simulations exceeding the microsecond timescale and the introduction of a co-solvent were used to characterize the pathways of the unfolding of a short DNA duplex. Two main pathways are detected involving different substrates. Once unfolding is reached the DNA adopts compact structures different from a random-coil distribution (see picture).
If you can't find a tool you're looking for, please click the link at the top of the page to "Go to old article view". Alternatively, view our Knowledge Base articles for additional help. Your feedback is important to us, so please let us know if you have comments or ideas for improvement.