This work was supported by the Excellent Young Scientists Foundation of Shandong Province (JQ200805), the University Doctoral Foundation of the Ministry of Education (200804260001), and the National Basic Research Program of China (2010CB732404).
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Communication
Colorimetric Logic Gates Based on Supramolecular DNAzyme Structures†
Article first published online: 7 MAY 2010
DOI: 10.1002/anie.201000840
Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Bi, S., Yan, Y., Hao, S. and Zhang, S. (2010), Colorimetric Logic Gates Based on Supramolecular DNAzyme Structures. Angew. Chem. Int. Ed., 49: 4438–4442. doi: 10.1002/anie.201000840
- †
Publication History
- Issue published online: 9 JUN 2010
- Article first published online: 7 MAY 2010
- Manuscript Revised: 19 MAR 2010
- Manuscript Received: 10 FEB 2010
Funded by
- Excellent Young Scientists Foundation of Shandong Province. Grant Number: JQ200805
- Ministry of Education. Grant Number: 200804260001
- National Basic Research Program of China. Grant Number: 2010CB732404
Keywords:
- aggregation;
- DNA structures;
- logic gates;
- molecular devices;
- nanoparticles
It′s logical! A set of DNAzyme-based Boolean logic gates consists of a series of supramolecular structures (see picture). Two metal ions (Mg2+ and Pb2+) act as inputs and gold nanoparticle (AuNP)/DNA probes as output reporters for colorimetric detection. Fast performance of the logic system at ambient temperature is achieved.