Pure Shift 1H NMR: A Resolution of the Resolution Problem?


  • We are grateful to the EPSRC for financial support of this work (grants EP/D05592X, EP/E057888/1, and EP/E05899X).


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Suppressing multiplet structure in 1H NMR spectra offers a large improvement in spectral resolution (see picture), equivalent to the use of a spectrometer in the GHz range. Such “pure shift” techniques are readily extended to multidimensional methods, for example DOSY.