High-Yielding Tandem Hydroformylation/Hydrogenation of a Terminal Olefin to Produce a Linear Alcohol Using a Rh/Ru Dual Catalyst System


  • This work was supported by KAKENHI (grant nos. 21245023 and 21685006) from MEXT (Japan).


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A dual catalyst system has been developed for tandem hydroformylation/hydrogenation to produce n-undecanol from 1-decene in one pot. A combination of xantphos/[Rh(acac)(CO)2] and Shvo's catalyst (1) afforded the best results (see scheme; acac=acetylacetonate, DMA=N,N-dimethylacetamide). Polar solvents effectively suppressed the formation of undecyl formate.