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Encapsulation of DNA-Templated Chromophore Assemblies within Virus Protein Nanotubes

Authors


  • We acknowledge funding from the IEF Marie Curie program of the European Union, the Chemical Council of the Netherlands Organization for Scientific Research (NWO), the EURYI Scheme of the European Science Foundation (ESF), and the Royal Netherlands Academy for Arts and Sciences. We also acknowledge Paul van der Schoot and E. W. (Bert) Meijer for useful discussions, and Koen Pieterse for the art work.

Abstract

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A beneficial virus: The hierarchical self-assembly of a three-component system consisting of single-stranded DNA (oligothymines; Tq), chromophores (G), and virus coat proteins (CP) leads to the formation of micrometer-long nanotubes (see picture). Tuning the interaction between the three components leads to the formation of structures with different length scales, and the chromophores within the nanotubes maintain the helical arrangement of the Tq–G template.

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