This work was supported financially by the National Institutes of Health (NIH) Director’s New Innovator Award Program, part of the NIH Roadmap for Medical Research, through grant number 1-DP2-OD002190-01, the Camille and Henry Dreyfus Foundation, and the Eastman Chemical Company (fellowship to A.J.Q.). We also thank Ji-Yeon Byeon for the SEM images of the microring resonator arrays.
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Communication
Multiplexed Detection and Label-Free Quantitation of MicroRNAs Using Arrays of Silicon Photonic Microring Resonators†
Article first published online: 20 MAY 2010
DOI: 10.1002/anie.201001712
Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Qavi, Abraham J. and Bailey, Ryan C. (2010), Multiplexed Detection and Label-Free Quantitation of MicroRNAs Using Arrays of Silicon Photonic Microring Resonators. Angew. Chem. Int. Ed., 49: 4608–4611. doi: 10.1002/anie.201001712
- †
Publication History
- Issue published online: 16 JUN 2010
- Article first published online: 20 MAY 2010
- Manuscript Received: 22 MAR 2010
Funded by
- National Institutes of Health (NIH). Grant Number: 1-DP2-OD002190-01
- Camille and Henry Dreyfus Foundation
Keywords:
- analytical methods;
- biosensors;
- oligonucleotides;
- RNA
Microrings for microRNAs! A label-free method has been developed for the sensitive detection of microRNAs utilizing arrays of silicon photonic microring resonators. This simple and modularly multiplexable method for the direct profiling of microRNA within 10 minutes meets a number of challenges faced by current methodologies in this area.